Nephrogenic Adenoma in the Setting of Refractory Labial Agglutination in an Elderly Woman

C. Emi Bretschneider*, Sarah M. Share, Marie Fidela R. Paraiso

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background Severe labial agglutination can be refractory to outpatient management and can lead to voiding dysfunction in postmenopausal women. Labial agglutination is often a sequela of long-standing inflammatory processes, which include untreated lichen planus, lichen sclerosus, and atrophic vaginitis. Case An 82-year-old parous woman presented with severe labial agglutination and complete obstruction of her vaginal introitus, causing obstructive voiding symptoms. She underwent a surgical procedure to release the fused labia. Pathologic evaluation of a vulvar biopsy revealed nephrogenic adenoma, which is an uncommon benign lesion usually presenting in the urinary tract. Conclusions Refractory, severe labial agglutination in postmenopausal women can lead to significant voiding dysfunction, and the underlying chronic inflammation may result in pathologic changes such as nephrogenic adenoma. Pathologic tissue diagnosis is important to plan appropriate surveillance for patients with this chronic condition.

Original languageEnglish (US)
Pages (from-to)e6-e8
JournalFemale Pelvic Medicine and Reconstructive Surgery
Issue number4
StatePublished - Jul 1 2018


  • agglutination
  • nephrogenic adenoma
  • voiding dysfunction

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology
  • Urology


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