Nephrotoxicity of xenobiotics

Mario Werner; Michael J. Costa; Lloyd G. Mitchell; Ritu Nayar

doi:10.1016/0009-8981(95)06068-O

Nephrotoxicity of xenobiotics

Mario Werner^*, Michael J. Costa, Lloyd G. Mitchell, Ritu Nayar

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol, D-penicillamine and methicillin is reviewed in light of all these three viewpoints, but emphasis is on toxic mechanisms.

Original language	English (US)
Pages (from-to)	107-154
Number of pages	48
Journal	Clinica Chimica Acta
Volume	237
Issue number	1-2
DOIs	https://doi.org/10.1016/0009-8981(95)06068-O
State	Published - Jun 15 1995

Keywords

Aminoglycosides
Cyclosporine
Demeclocycline
Ethylene glycol
Lithium
Mercury
Methicillin
Methoxyflurane
Nonsteroidal anti-inflammatory drugs
d-penicillamine

ASJC Scopus subject areas

Biochemistry, medical
Biochemistry
Clinical Biochemistry

Access to Document

10.1016/0009-8981(95)06068-O

Cite this

@article{4915e228c98a47c6a41e92848d2f683b,

title = "Nephrotoxicity of xenobiotics",

abstract = "Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol, D-penicillamine and methicillin is reviewed in light of all these three viewpoints, but emphasis is on toxic mechanisms.",

keywords = "Aminoglycosides, Cyclosporine, Demeclocycline, Ethylene glycol, Lithium, Mercury, Methicillin, Methoxyflurane, Nonsteroidal anti-inflammatory drugs, d-penicillamine",

author = "Mario Werner and Costa, {Michael J.} and Mitchell, {Lloyd G.} and Ritu Nayar",

year = "1995",

month = jun,

day = "15",

doi = "10.1016/0009-8981(95)06068-O",

language = "English (US)",

volume = "237",

pages = "107--154",

journal = "Clinica Chimica Acta",

issn = "0009-8981",

publisher = "Elsevier B.V.",

number = "1-2",

}

TY - JOUR

T1 - Nephrotoxicity of xenobiotics

AU - Werner, Mario

AU - Costa, Michael J.

AU - Mitchell, Lloyd G.

AU - Nayar, Ritu

PY - 1995/6/15

Y1 - 1995/6/15

N2 - Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol, D-penicillamine and methicillin is reviewed in light of all these three viewpoints, but emphasis is on toxic mechanisms.

AB - Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol, D-penicillamine and methicillin is reviewed in light of all these three viewpoints, but emphasis is on toxic mechanisms.

KW - Aminoglycosides

KW - Cyclosporine

KW - Demeclocycline

KW - Ethylene glycol

KW - Lithium

KW - Mercury

KW - Methicillin

KW - Methoxyflurane

KW - Nonsteroidal anti-inflammatory drugs

KW - d-penicillamine

UR - http://www.scopus.com/inward/record.url?scp=0029053271&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029053271&partnerID=8YFLogxK

U2 - 10.1016/0009-8981(95)06068-O

DO - 10.1016/0009-8981(95)06068-O

M3 - Article

C2 - 7664472

AN - SCOPUS:0029053271

SN - 0009-8981

VL - 237

SP - 107

EP - 154

JO - Clinica Chimica Acta

JF - Clinica Chimica Acta

IS - 1-2

ER -

Nephrotoxicity of xenobiotics

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this