Network Control

D. R. McCrimmon*, G. S. Mitchell, J. L. Feldman, G. F. Alheid

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


Breathing is a voluntary somatic motor behavior. Brain stem circuits generate a respiratory rhythm and dynamically adapt the pattern of activity on respiratory pump and airway muscles to meet the wide range of metabolic demands experienced by an individual vertebrate animal. This article describes the neuronal elements and brain stem compartments that make up the respiratory control system in the rhombencephalon (hind brain) in mammals. It also surveys respiratory reflexes and their associated brain stem circuitry that provide for the dynamic regulation of normal breathing and for the protective reflexes that preserve airway integrity.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd
Number of pages11
ISBN (Print)9780080450469
StatePublished - Jan 1 2009


  • Brain stem circuitry
  • Bötzinger complex
  • Chemoreceptor
  • Medulla
  • Motor control
  • Pattern generation
  • Pons
  • Pre-Bötzinger complex
  • Pulmonary stretch receptors
  • Rapidly adapting receptor
  • Regulation of breathing
  • Respiratory reflexes
  • Retrotrapezoid nucleus
  • Rhombencephalon
  • Vagus nerve

ASJC Scopus subject areas

  • Neuroscience(all)


Dive into the research topics of 'Network Control'. Together they form a unique fingerprint.

Cite this