Neural correlates of preserved facial affect perception in high functioning schizophrenia

Tatiana M. Karpouzian; Matthew P. Schroeder; Samantha V. Abram; Harry Wanar; Eva C. Alden; Shaun M. Eack; John G. Csernansky; Matthew J. Smith

doi:10.1016/j.pscychresns.2017.06.002

Neural correlates of preserved facial affect perception in high functioning schizophrenia

Tatiana M. Karpouzian, Matthew P. Schroeder, Samantha V. Abram, Harry Wanar, Eva C. Alden, Shaun M. Eack, John G. Csernansky, Matthew J. Smith^*

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Individuals with ‘high functioning’ schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with ‘low functioning’ schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups.

Original language	English (US)
Pages (from-to)	83-85
Number of pages	3
Journal	Psychiatry Research - Neuroimaging
Volume	266
DOIs	https://doi.org/10.1016/j.pscychresns.2017.06.002
State	Published - Aug 30 2017

Keywords

Community functioning
Facial accept perception
Schizophrenia

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pscychresns.2017.06.002

Cite this

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title = "Neural correlates of preserved facial affect perception in high functioning schizophrenia",

abstract = "Individuals with {\textquoteleft}high functioning{\textquoteright} schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with {\textquoteleft}low functioning{\textquoteright} schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups.",

keywords = "Community functioning, Facial accept perception, Schizophrenia",

author = "Karpouzian, {Tatiana M.} and Schroeder, {Matthew P.} and Abram, {Samantha V.} and Harry Wanar and Alden, {Eva C.} and Eack, {Shaun M.} and Csernansky, {John G.} and Smith, {Matthew J.}",

note = "Funding Information: Funding: This study was supported by the Department of Psychiatry and Behavioral Sciences at the Northwestern University Feinberg School of Medicine and a grant from the National Institute of Mental Health (NIMH) to Dr. Csernansky (R01 MH056584). NIMH had no role in the study design, collection, analysis or interpretation of data, writing the manuscript, or the decision to submit the paper for publication. Publisher Copyright: {\textcopyright} 2017 Elsevier Ireland Ltd",

year = "2017",

month = aug,

day = "30",

doi = "10.1016/j.pscychresns.2017.06.002",

language = "English (US)",

volume = "266",

pages = "83--85",

journal = "Psychiatry Research - Neuroimaging",

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publisher = "Elsevier Ireland Ltd",

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TY - JOUR

T1 - Neural correlates of preserved facial affect perception in high functioning schizophrenia

AU - Karpouzian, Tatiana M.

AU - Schroeder, Matthew P.

AU - Abram, Samantha V.

AU - Wanar, Harry

AU - Alden, Eva C.

AU - Eack, Shaun M.

AU - Csernansky, John G.

AU - Smith, Matthew J.

N1 - Funding Information: Funding: This study was supported by the Department of Psychiatry and Behavioral Sciences at the Northwestern University Feinberg School of Medicine and a grant from the National Institute of Mental Health (NIMH) to Dr. Csernansky (R01 MH056584). NIMH had no role in the study design, collection, analysis or interpretation of data, writing the manuscript, or the decision to submit the paper for publication. Publisher Copyright: © 2017 Elsevier Ireland Ltd

PY - 2017/8/30

Y1 - 2017/8/30

N2 - Individuals with ‘high functioning’ schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with ‘low functioning’ schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups.

AB - Individuals with ‘high functioning’ schizophrenia (HF-SCZ) may have preserved facial affect perception (FAP) compared to individuals with ‘low functioning’ schizophrenia (LF-SCZ). The neural mechanisms supporting preserved FAP in HF-SCZ have yet to be evaluated. This study compared brain activation during FAP performance in HF-SCZ, LF-SCZ, and controls. Results demonstrated greater activation in the precuneus in CON compared to both SCZ groups, while HF-SCZ activated this region intermediate to controls and LF-SCZ. These preliminary findings suggest greater precuneus activation may be related to preserved FAP in HF-SCZ compared to LF-SCZ, though future research is needed to further evaluate differences between groups.

KW - Community functioning

KW - Facial accept perception

KW - Schizophrenia

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Neural correlates of preserved facial affect perception in high functioning schizophrenia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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