Neural Correlates of Sensory Hyporesponsiveness in Toddlers at High Risk for Autism Spectrum Disorder

David M. Simon, Cara R. Damiano, Tiffany G. Woynaroski, Lisa V. Ibañez, Michael Andrew Murias, Wendy L. Stone, Mark T. Wallace, Carissa J. Cascio*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Altered patterns of sensory responsiveness are a frequently reported feature of Autism Spectrum Disorder (ASD). Younger siblings of individuals with ASD are at a greatly elevated risk of a future diagnosis of ASD, but little is known about the neural basis of sensory responsiveness patterns in this population. Younger siblings (n = 20) of children diagnosed with ASD participated in resting electroencephalography (EEG) at an age of 18 months. Data on toddlers’ sensory responsiveness were obtained using the Sensory Experiences Questionnaire. Correlations were present between hyporesponsiveness and patterns of oscillatory power, functional connectivity, and signal complexity. Our findings suggest that neural signal features hold promise for facilitating early identification and targeted remediation in young children at risk for ASD.

Original languageEnglish (US)
Pages (from-to)2710-2722
Number of pages13
JournalJournal of Autism and Developmental Disorders
Volume47
Issue number9
DOIs
StatePublished - Sep 1 2017

Keywords

  • Autism spectrum disorder
  • Electroencephalogram (EEG)
  • Frontal EEG asymmetry
  • Functional connectivity
  • Infant siblings
  • Sensory hyporesponsiveness

ASJC Scopus subject areas

  • Developmental and Educational Psychology

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