Abstract
The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural variability. These neural manifolds are spanned by specific patterns of correlated neural activity, the “neural modes.” We discuss a model for neural control of movement in which the time-dependent activation of these neural modes is the generator of motor behavior. This manifold-based view of motor cortex may lead to a better understanding of how the brain controls movement.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 978-984 |
| Number of pages | 7 |
| Journal | Neuron |
| Volume | 94 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jun 7 2017 |
Funding
This work was supported in part by Grant NS053603 from the National Institute of Neurological Disorder and Stroke (L.E.M.), by Grant NS094748 from the National Institute of Neurological Disorder and Stroke (S.A.S.), by Grant FP7-PEOPLE-2013-IOF-627384 from the Commission of the European Union (J.A.G.), and by Grant F31-NS092356 from the National Institute of Neurological Disorder and Stroke and Grant T32-HD07418 from the National Center for Medical Rehabilitation Research (M.G.P.). We thank Carolina Massumoto for the monkey illustration.
ASJC Scopus subject areas
- General Neuroscience