Neural mechanisms of discourse comprehension: A human lesion study

Aron K. Barbey*, Roberto Colom, Jordan Grafman

*Corresponding author for this work

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Discourse comprehension is a hallmark of human social behaviour and refers to the act of interpreting a written or spoken message by constructing mental representations that integrate incoming language with prior knowledge and experience. Here, we report a human lesion study (n = 145) that investigates the neural mechanisms underlying discourse comprehension (measured by the Discourse Comprehension Test) and systematically examine its relation to a broad range of psychological factors, including psychometric intelligence (measured by the Wechsler Adult Intelligence Scale), emotional intelligence (measured by the Mayer, Salovey, Caruso Emotional Intelligence Test), and personality traits (measured by the Neuroticism-Extraversion-Openness Personality Inventory). Scores obtained from these factors were submitted to voxel-based lesion-symptom mapping to elucidate their neural substrates. Stepwise regression analyses revealed that working memory and extraversion reliably predict individual differences in discourse comprehension: higher working memory scores and lower extraversion levels predict better discourse comprehension performance. Lesion mapping results indicated that these convergent variables depend on a shared network of frontal and parietal regions, including white matter association tracts that bind these areas into a coordinated system. The observed findings motivate an integrative framework for understanding the neural foundations of discourse comprehension, suggesting that core elements of discourse processing emerge from a distributed network of brain regions that support specific competencies for executive and social function.

Original languageEnglish (US)
Pages (from-to)277-287
Number of pages11
JournalBrain
Volume137
Issue number1
DOIs
StatePublished - Jan 2014

Fingerprint

Emotional Intelligence
Intelligence
Short-Term Memory
Personality Inventory
Parietal Lobe
Intelligence Tests
Social Behavior
Executive Function
Psychometrics
Individuality
Personality
Language
Regression Analysis
Psychology
Brain
Extraversion (Psychology)
White Matter
Neuroticism

Keywords

  • discourse comprehension
  • emotional intelligence
  • personality traits
  • psychometric intelligence
  • voxel-based lesion-symptom mapping

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Barbey, Aron K. ; Colom, Roberto ; Grafman, Jordan. / Neural mechanisms of discourse comprehension : A human lesion study. In: Brain. 2014 ; Vol. 137, No. 1. pp. 277-287.
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Neural mechanisms of discourse comprehension : A human lesion study. / Barbey, Aron K.; Colom, Roberto; Grafman, Jordan.

In: Brain, Vol. 137, No. 1, 01.2014, p. 277-287.

Research output: Contribution to journalArticle

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