Neurobiology of sleep

Brandon S. Lu; Phyllis C. Zee

doi:10.1016/j.ccm.2010.02.004

Neurobiology of sleep

Brandon S. Lu^*, Phyllis C. Zee

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Abstract

The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented.

Original language	English (US)
Pages (from-to)	309-318
Number of pages	10
Journal	Clinics in Chest Medicine
Volume	31
Issue number	2
DOIs	https://doi.org/10.1016/j.ccm.2010.02.004
State	Published - Jun 2010

Keywords

Sleep disorders
Sleep neurobiology
Sleep regulation
Sleep-wake transition

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.ccm.2010.02.004

Cite this

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title = "Neurobiology of sleep",

abstract = "The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented.",

keywords = "Sleep disorders, Sleep neurobiology, Sleep regulation, Sleep-wake transition",

author = "Lu, \{Brandon S.\} and Zee, \{Phyllis C.\}",

year = "2010",

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AU - Zee, Phyllis C.

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AB - The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented.

KW - Sleep disorders

KW - Sleep neurobiology

KW - Sleep regulation

KW - Sleep-wake transition

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DO - 10.1016/j.ccm.2010.02.004

M3 - Review article

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JF - Clinics in Chest Medicine

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ER -

Neurobiology of sleep

Abstract

Keywords

ASJC Scopus subject areas

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