Neurocognitive function in moderate–severe pediatric atopic dermatitis: A case–control study

Lacey L. Kruse*, Ahuva Cices, Anna B. Fishbein, Amy S. Paller

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background/Objectives: Epidemiological studies have shown an increased prevalence of attention deficit hyperactivity disorder (ADHD) in children with atopic dermatitis (AD), but many of the features of ADHD may occur as a result of the poor sleep and itch distraction associated with AD. Methods: A case–control study was performed in children aged 6-17 years with moderate/severe AD compared with age-/sex-matched healthy controls. Participants were screened for ADHD using Vanderbilt assessments. Results: Seventeen patients with AD and 18 controls completed the study. Two children with AD (11.7%) and one control (5.56%) met screening criteria for ADHD via parent-completed Vanderbilt assessments; AD patients were not significantly more likely to screen positive for ADHD (P = 0.47), or comorbid behavior disorders (P = 0.23). However, AD patients were more likely than controls to exhibit ADHD-associated behaviors, most significantly inattention. Conclusions: Our AD cohort did not have a significantly increased prevalence of ADHD. Certain neurocognitive symptoms are increased in children with moderate-to-severe AD compared to controls.

Original languageEnglish (US)
Pages (from-to)110-114
Number of pages5
JournalPediatric dermatology
Volume36
Issue number1
DOIs
Publication statusPublished - Jan 1 2019

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Keywords

  • atopic dermatitis
  • attention deficit hyperactivity disorder
  • behavior
  • inattention
  • neurocognitive
  • sleep
  • sleep disturbance

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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