Abstract
This literature review summarizes all studies relating neuropsychological performance to neuroimaging findings in pediatric sickle cell disease (N=28; published 1991-2005). Although inconsistencies exist within and across domains, deficits in intelligence (IQ), attention and executive functions, memory, language, visuomotor abilities, and academic achievement have been identified. Overall neurocognitive compromise was revealed to be related to the level of neurological injury and the location of silent infarct. Attentional and executive dysfunction is prevalent and related to frontal lobe abnormalities.
Original language | English (US) |
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Pages (from-to) | 120-131 |
Number of pages | 12 |
Journal | Child Neuropsychology |
Volume | 13 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2007 |
Keywords
- Children
- Cognitive rehabilitation
- Executive function
- Literature review
- Neuroimaging
- Pediatric neuropsychology
- Sickle cell disease
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Neuropsychology and Physiological Psychology
- Developmental and Educational Psychology