Abstract
Although schizophrenia is primarily considered to be a neurodevelopmental disorder, there is a growing consensus that the disorder may also involve neurodegeneration. Recent research using non-invasive neuroimaging techniques, such as magnetic resonance imaging, suggests that some patients with schizophrenia show progressive losses of gray matter in the frontal and temporal lobes of the brain. The cellular mechanisms responsible for such gray matter losses are unknown, but have been hypothesized to involve abnormal increases in apoptosis.
Original language | English (US) |
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Pages (from-to) | 135-143 |
Number of pages | 9 |
Journal | TheScientificWorldJournal |
Volume | 7 |
DOIs | |
State | Published - Feb 2 2007 |
Keywords
- Apoptosis
- Glutamate
- Neurodegeneration
- Neuroimaging
- Schizophrenia
ASJC Scopus subject areas
- Environmental Science(all)
- Biochemistry, Genetics and Molecular Biology(all)