Neurogenic and nonneurogenic pain and inflammatory mediators

James Neil Weinstein*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Neuropeptides may play a significant role in degenerative spine disease. This article discusses the gate control theory of pain and the role of neuropeptides in the degeneration of the functional spinal unit. Our current understanding of pain, its perception and modulation, is basic and requires more research.

Original languageEnglish (US)
Pages (from-to)235-246
Number of pages12
JournalOrthopedic Clinics of North America
Issue number2
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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