Neurogenic pulmonary edema and acute respiratory distress syndrome in a healthy child with febrile status epilepticus

Thanh T. Nguyen, Elora Hussain, Michele Grimason, Joshua Goldstein, Mark S. Wainwright*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Neurogenic pulmonary edema is a clinical syndrome that manifests as an acute onset of pulmonary edema in the setting of a central nervous system injury, without cardiac dysfunction. Neurogenic pulmonary edema is rare in children, and the mechanism is still not completely understood. The clinical pathology overlaps with acute lung injury and acute respiratory distress syndrome. The authors report a case of a 14-month-old previously healthy child who presented with febrile status epilepticus, fulminant neurogenic pulmonary edema, and acute respiratory distress syndrome. Neurogenic pulmonary edema should be considered in the differential diagnosis for the rapid progression of respiratory failure following an acute neurological injury such as status epilepticus in a child. Prompt respiratory support and treatment of the acute neurological insult can prevent further cerebral hypoxemic injury.

Original languageEnglish (US)
Pages (from-to)1287-1291
Number of pages5
JournalJournal of child neurology
Volume28
Issue number10
DOIs
StatePublished - Oct 1 2013

Keywords

  • acute respiratory distress syndrome
  • neurogenic pulmonary edema
  • status epilepticus

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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