Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence

Elaine F. Walker; Amanda McMillan; Vijay Mittal

doi:10.1093/acprof:oso/9780195306255.003.0012

Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence

Elaine F. Walker^*, Amanda McMillan, Vijay Mittal

^*Corresponding author for this work

Psychology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

It has been suggested that the neural systems governing the response to stress, especially the hypothalamic-pituitary-adrenal (HPA) axis, may function to augment the expression of the core vulnerability to psychosis. This chapter reviews research findings that bear on adolescent vulnerability for psychosis and neurodevelopment of the HPA-hippocampal system, with an emphasis on implications for preventive intervention. The chapter presents preliminary data from recent research that suggests how psychopharmacologic interventions might alter HPA function, and thereby modify the transition to psychosis in at-risk adolescents.

Original language	English (US)
Title of host publication	Adolescent Psychopathology and the Developing Brain
Subtitle of host publication	Integrating Brain and Prevention Science
Publisher	Oxford University Press
ISBN (Electronic)	9780199863914
ISBN (Print)	0195306260, 9780195306255
DOIs	https://doi.org/10.1093/acprof:oso/9780195306255.003.0012
State	Published - Mar 22 2007

Keywords

HPA function
Hypothalamic-pituitary-adrenal axis
Psychosis
Stress

ASJC Scopus subject areas

Neuroscience(all)

Access to Document

10.1093/acprof:oso/9780195306255.003.0012

Fingerprint Dive into the research topics of 'Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence'. Together they form a unique fingerprint.

Cite this

@inbook{7ef3e9ab02f84bc9b5f4409384b4f312,

title = "Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence",

abstract = "It has been suggested that the neural systems governing the response to stress, especially the hypothalamic-pituitary-adrenal (HPA) axis, may function to augment the expression of the core vulnerability to psychosis. This chapter reviews research findings that bear on adolescent vulnerability for psychosis and neurodevelopment of the HPA-hippocampal system, with an emphasis on implications for preventive intervention. The chapter presents preliminary data from recent research that suggests how psychopharmacologic interventions might alter HPA function, and thereby modify the transition to psychosis in at-risk adolescents.",

keywords = "HPA function, Hypothalamic-pituitary-adrenal axis, Psychosis, Stress",

author = "Walker, {Elaine F.} and Amanda McMillan and Vijay Mittal",

year = "2007",

month = mar,

day = "22",

doi = "10.1093/acprof:oso/9780195306255.003.0012",

language = "English (US)",

isbn = "0195306260",

booktitle = "Adolescent Psychopathology and the Developing Brain",

publisher = "Oxford University Press",

}

TY - CHAP

T1 - Neurohormones, Neurodevelopment, and the Prodrome of Psychosis in Adolescence

AU - Walker, Elaine F.

AU - McMillan, Amanda

AU - Mittal, Vijay

PY - 2007/3/22

Y1 - 2007/3/22

N2 - It has been suggested that the neural systems governing the response to stress, especially the hypothalamic-pituitary-adrenal (HPA) axis, may function to augment the expression of the core vulnerability to psychosis. This chapter reviews research findings that bear on adolescent vulnerability for psychosis and neurodevelopment of the HPA-hippocampal system, with an emphasis on implications for preventive intervention. The chapter presents preliminary data from recent research that suggests how psychopharmacologic interventions might alter HPA function, and thereby modify the transition to psychosis in at-risk adolescents.

AB - It has been suggested that the neural systems governing the response to stress, especially the hypothalamic-pituitary-adrenal (HPA) axis, may function to augment the expression of the core vulnerability to psychosis. This chapter reviews research findings that bear on adolescent vulnerability for psychosis and neurodevelopment of the HPA-hippocampal system, with an emphasis on implications for preventive intervention. The chapter presents preliminary data from recent research that suggests how psychopharmacologic interventions might alter HPA function, and thereby modify the transition to psychosis in at-risk adolescents.

KW - HPA function

KW - Hypothalamic-pituitary-adrenal axis

KW - Psychosis

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=84918914866&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918914866&partnerID=8YFLogxK

U2 - 10.1093/acprof:oso/9780195306255.003.0012

DO - 10.1093/acprof:oso/9780195306255.003.0012

M3 - Chapter

AN - SCOPUS:84918914866

SN - 0195306260

SN - 9780195306255

BT - Adolescent Psychopathology and the Developing Brain

PB - Oxford University Press

ER -