Neurological management of von Hippel-Lindau disease

Trent S. Hodgson; Sarah M. Nielsen; Maciej S. Lesniak; Rimas V. Lukas

doi:10.1097/NRL.0000000000000085

Neurological management of von Hippel-Lindau disease

Trent S. Hodgson, Sarah M. Nielsen, Maciej S. Lesniak, Rimas V. Lukas^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Von Hippel-Lindau disease is a genetic condition due to mutation of the Von Hippel-Lindau gene, which leads to an increased risk in the development of hemangioblastomas of the brain and spinal cord. The pathophysiology of disease and its clinical manifestations, as they pertain to the general neurologist, are discussed. Therapeutic management of central nervous system hemangioblastomas ranging from neurosurgical resection, radiation therapy, and systemic therapies is reviewed.

Original language	English (US)
Pages (from-to)	73-78
Number of pages	6
Journal	Neurologist
Volume	21
Issue number	5
DOIs	https://doi.org/10.1097/NRL.0000000000000085
State	Published - 2016

Keywords

Von Hippel-Lindau disease
brain
central nervous system
hemangioblastoma
spinal cord

ASJC Scopus subject areas

Clinical Neurology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/NRL.0000000000000085

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title = "Neurological management of von Hippel-Lindau disease",

abstract = "Von Hippel-Lindau disease is a genetic condition due to mutation of the Von Hippel-Lindau gene, which leads to an increased risk in the development of hemangioblastomas of the brain and spinal cord. The pathophysiology of disease and its clinical manifestations, as they pertain to the general neurologist, are discussed. Therapeutic management of central nervous system hemangioblastomas ranging from neurosurgical resection, radiation therapy, and systemic therapies is reviewed.",

keywords = "Von Hippel-Lindau disease, brain, central nervous system, hemangioblastoma, spinal cord",

author = "Hodgson, {Trent S.} and Nielsen, {Sarah M.} and Lesniak, {Maciej S.} and Lukas, {Rimas V.}",

note = "Publisher Copyright: {\textcopyright} 2016 Wolters Kluwer Health, Inc.",

year = "2016",

doi = "10.1097/NRL.0000000000000085",

language = "English (US)",

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TY - JOUR

T1 - Neurological management of von Hippel-Lindau disease

AU - Hodgson, Trent S.

AU - Nielsen, Sarah M.

AU - Lesniak, Maciej S.

AU - Lukas, Rimas V.

PY - 2016

Y1 - 2016

N2 - Von Hippel-Lindau disease is a genetic condition due to mutation of the Von Hippel-Lindau gene, which leads to an increased risk in the development of hemangioblastomas of the brain and spinal cord. The pathophysiology of disease and its clinical manifestations, as they pertain to the general neurologist, are discussed. Therapeutic management of central nervous system hemangioblastomas ranging from neurosurgical resection, radiation therapy, and systemic therapies is reviewed.

AB - Von Hippel-Lindau disease is a genetic condition due to mutation of the Von Hippel-Lindau gene, which leads to an increased risk in the development of hemangioblastomas of the brain and spinal cord. The pathophysiology of disease and its clinical manifestations, as they pertain to the general neurologist, are discussed. Therapeutic management of central nervous system hemangioblastomas ranging from neurosurgical resection, radiation therapy, and systemic therapies is reviewed.

KW - Von Hippel-Lindau disease

KW - brain

KW - central nervous system

KW - hemangioblastoma

KW - spinal cord

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AN - SCOPUS:84987792413

SN - 1074-7931

VL - 21

SP - 73

EP - 78

JO - Neurologist

JF - Neurologist

IS - 5

ER -

Neurological management of von Hippel-Lindau disease

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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