Neurological management of von Hippel-Lindau disease

Trent S. Hodgson, Sarah M. Nielsen, Maciej S. Lesniak, Rimas V. Lukas*

*Corresponding author for this work

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Von Hippel-Lindau disease is a genetic condition due to mutation of the Von Hippel-Lindau gene, which leads to an increased risk in the development of hemangioblastomas of the brain and spinal cord. The pathophysiology of disease and its clinical manifestations, as they pertain to the general neurologist, are discussed. Therapeutic management of central nervous system hemangioblastomas ranging from neurosurgical resection, radiation therapy, and systemic therapies is reviewed.

Original languageEnglish (US)
Pages (from-to)73-78
Number of pages6
JournalNeurologist
Volume21
Issue number5
DOIs
StatePublished - Jan 1 2016

Keywords

  • Von Hippel-Lindau disease
  • brain
  • central nervous system
  • hemangioblastoma
  • spinal cord

ASJC Scopus subject areas

  • Clinical Neurology

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