Neuromuscular adaptations during 30 days of cast-immobilization and head-down bedrest.

M. M. Jaweed*, E. A. Grana, T. P. Glennon, T. N. Monga, B. Mirabi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Prolonged skeletal muscle disuse, during space flights and on Earth, produces distinct adaptive changes in the neuromuscular system of human subjects. There is a significant decline in muscle mass and strength, exercise capacity, fatigue resistance, integrated EMG (IEMG) output and time-dependent alterations in the behavior of Hoffman (H) and deep tendon reflexes. The objective of this study was to examine the changes in excitability of segmental motoneuronal network and its influence upon gastrocnemius-soleus (G-S) function in healthy male and female subjects, who underwent either 6 degrees head-down bedrest (HDB) or unilateral cast-immobilization (CIM) for a period of 30 days.

Original languageEnglish (US)
Pages (from-to)P72-73
JournalJournal of gravitational physiology : a journal of the International Society for Gravitational Physiology
Issue number1
StatePublished - 1995

ASJC Scopus subject areas

  • General Medicine


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