Neuron activity in rat hippocampus and motor cortex during discrimination reversal

John F. Disterhoft*, Menahem Segal

*Corresponding author for this work

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

DISTERHOFT, J. F. AND M. SEGAL. Neuron activity in rat hippocampus and motor cortex during discrimination reversal. BRAIN RES. BULL. 3(6) 583-588, 1978.-Chronic unit activity and gross movement were recorded from rats during two discrimination reversals in a classical appetitive conditioning situation. The anticipatory movement decreased in response to the former CS+ tone and increased to the previous CS- tone after each reversal. Hippocampus and motor cortex were differently related to these two kinds of behavioral change. Response rates of hippocampal neurons were more closely related to the increased movement response to the former CS- which now signaled food. Motor cortex neuron responses were more closely correlated with the decrease in movement responses to the former CS+ which became neutral after the reversal. It appeared that hippocampal neurons could have been involved in one cognitive aspect of the situation, motor cortex neurons in another. The data were related to current functional concepts of these brain regions.

Original languageEnglish (US)
Pages (from-to)583-588
Number of pages6
JournalBrain Research Bulletin
Volume3
Issue number6
DOIs
StatePublished - Jan 1 1978

Keywords

  • Cortex
  • Discrimination reversal
  • Hippocampus
  • Units

ASJC Scopus subject areas

  • Neuroscience(all)

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