Neuropeptides within the nucleus tractus solitarii modulate the central cardiovascular control process

A. Brattstrom, M. Sonntag, H. Listing, R. Miller, W. DeJong

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Local administration of small amounts of vasopressin, angiotensin or endothelin into the nucleus tractus solitarii elicits similar decreases in blood pressure and heart rate. These central effects oppose the peripheral action of these hormones on the cardiovascular system. The baroreceptor-heart-reflex, however, is influenced differentially: vasopressin and angiotensin II enhances the sensitivity of the reflex but angiotensin III impairs it. In this way the cardiovascular system may be adjusted to different demands including those related to electrolyte and fluid homeostasis.

Original languageEnglish (US)
Pages (from-to)75-79
Number of pages5
JournalProgress in brain research
Volume91
Issue numberC
DOIs
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • General Neuroscience

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