Neuroticism as a common dimension in the internalizing disorders

James W Griffith, Richard E Zinbarg, M. G. Craske, Susan Mineka, R. D. Rose, A. M. Waters, J. M. Sutton

Research output: Contribution to journalArticle

145 Citations (Scopus)

Abstract

Background Several theories have posited a common internalizing factor to help account for the relationship between mood and anxiety disorders. These disorders are often co-morbid and strongly covary. Other theories and data suggest that personality traits may account, at least in part, for co-morbidity between depression and anxiety. The present study examined the relationship between neuroticism and an internalizing dimension common to mood and anxiety disorders.Method A sample of ethnically diverse adolescents (n=621) completed self-report and peer-report measures of neuroticism. Participants also completed the Structured Clinical Interview for DSM-IV (SCID).Results Structural equation modeling showed that a single internalizing factor was common to lifetime diagnosis of mood and anxiety disorders, and this internalizing factor was strongly correlated with neuroticism. Neuroticism had a stronger correlation with an internalizing factor (r=0.98) than with a substance use factor (r=0.29). Therefore, neuroticism showed both convergent and discriminant validity.Conclusions These results provide further evidence that neuroticism is a necessary factor in structural theories of mood and anxiety disorders. In this study, the correlation between internalizing psychopathology and neuroticism approached 1.0, suggesting that neuroticism may be the core of internalizing psychopathology. Future studies are needed to examine this possibility in other populations, and to replicate our findings.

Original languageEnglish (US)
Pages (from-to)1125-1136
Number of pages12
JournalPsychological Medicine
Volume40
Issue number7
DOIs
StatePublished - Jul 1 2010

Fingerprint

Anxiety Disorders
Mood Disorders
Psychopathology
Neuroticism
Diagnostic and Statistical Manual of Mental Disorders
Self Report
Personality
Anxiety
Interviews
Depression
Morbidity
Population

Keywords

  • Anxiety disorders
  • Co-morbidity
  • Neuroticism
  • Unipolar mood disorders

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health

Cite this

Griffith, James W ; Zinbarg, Richard E ; Craske, M. G. ; Mineka, Susan ; Rose, R. D. ; Waters, A. M. ; Sutton, J. M. / Neuroticism as a common dimension in the internalizing disorders. In: Psychological Medicine. 2010 ; Vol. 40, No. 7. pp. 1125-1136.
@article{c5bd1f67b6af492ca1159bf47ff726af,
title = "Neuroticism as a common dimension in the internalizing disorders",
abstract = "Background Several theories have posited a common internalizing factor to help account for the relationship between mood and anxiety disorders. These disorders are often co-morbid and strongly covary. Other theories and data suggest that personality traits may account, at least in part, for co-morbidity between depression and anxiety. The present study examined the relationship between neuroticism and an internalizing dimension common to mood and anxiety disorders.Method A sample of ethnically diverse adolescents (n=621) completed self-report and peer-report measures of neuroticism. Participants also completed the Structured Clinical Interview for DSM-IV (SCID).Results Structural equation modeling showed that a single internalizing factor was common to lifetime diagnosis of mood and anxiety disorders, and this internalizing factor was strongly correlated with neuroticism. Neuroticism had a stronger correlation with an internalizing factor (r=0.98) than with a substance use factor (r=0.29). Therefore, neuroticism showed both convergent and discriminant validity.Conclusions These results provide further evidence that neuroticism is a necessary factor in structural theories of mood and anxiety disorders. In this study, the correlation between internalizing psychopathology and neuroticism approached 1.0, suggesting that neuroticism may be the core of internalizing psychopathology. Future studies are needed to examine this possibility in other populations, and to replicate our findings.",
keywords = "Anxiety disorders, Co-morbidity, Neuroticism, Unipolar mood disorders",
author = "Griffith, {James W} and Zinbarg, {Richard E} and Craske, {M. G.} and Susan Mineka and Rose, {R. D.} and Waters, {A. M.} and Sutton, {J. M.}",
year = "2010",
month = "7",
day = "1",
doi = "10.1017/S0033291709991449",
language = "English (US)",
volume = "40",
pages = "1125--1136",
journal = "Psychological Medicine",
issn = "0033-2917",
publisher = "Cambridge University Press",
number = "7",

}

Neuroticism as a common dimension in the internalizing disorders. / Griffith, James W; Zinbarg, Richard E; Craske, M. G.; Mineka, Susan; Rose, R. D.; Waters, A. M.; Sutton, J. M.

In: Psychological Medicine, Vol. 40, No. 7, 01.07.2010, p. 1125-1136.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Neuroticism as a common dimension in the internalizing disorders

AU - Griffith, James W

AU - Zinbarg, Richard E

AU - Craske, M. G.

AU - Mineka, Susan

AU - Rose, R. D.

AU - Waters, A. M.

AU - Sutton, J. M.

PY - 2010/7/1

Y1 - 2010/7/1

N2 - Background Several theories have posited a common internalizing factor to help account for the relationship between mood and anxiety disorders. These disorders are often co-morbid and strongly covary. Other theories and data suggest that personality traits may account, at least in part, for co-morbidity between depression and anxiety. The present study examined the relationship between neuroticism and an internalizing dimension common to mood and anxiety disorders.Method A sample of ethnically diverse adolescents (n=621) completed self-report and peer-report measures of neuroticism. Participants also completed the Structured Clinical Interview for DSM-IV (SCID).Results Structural equation modeling showed that a single internalizing factor was common to lifetime diagnosis of mood and anxiety disorders, and this internalizing factor was strongly correlated with neuroticism. Neuroticism had a stronger correlation with an internalizing factor (r=0.98) than with a substance use factor (r=0.29). Therefore, neuroticism showed both convergent and discriminant validity.Conclusions These results provide further evidence that neuroticism is a necessary factor in structural theories of mood and anxiety disorders. In this study, the correlation between internalizing psychopathology and neuroticism approached 1.0, suggesting that neuroticism may be the core of internalizing psychopathology. Future studies are needed to examine this possibility in other populations, and to replicate our findings.

AB - Background Several theories have posited a common internalizing factor to help account for the relationship between mood and anxiety disorders. These disorders are often co-morbid and strongly covary. Other theories and data suggest that personality traits may account, at least in part, for co-morbidity between depression and anxiety. The present study examined the relationship between neuroticism and an internalizing dimension common to mood and anxiety disorders.Method A sample of ethnically diverse adolescents (n=621) completed self-report and peer-report measures of neuroticism. Participants also completed the Structured Clinical Interview for DSM-IV (SCID).Results Structural equation modeling showed that a single internalizing factor was common to lifetime diagnosis of mood and anxiety disorders, and this internalizing factor was strongly correlated with neuroticism. Neuroticism had a stronger correlation with an internalizing factor (r=0.98) than with a substance use factor (r=0.29). Therefore, neuroticism showed both convergent and discriminant validity.Conclusions These results provide further evidence that neuroticism is a necessary factor in structural theories of mood and anxiety disorders. In this study, the correlation between internalizing psychopathology and neuroticism approached 1.0, suggesting that neuroticism may be the core of internalizing psychopathology. Future studies are needed to examine this possibility in other populations, and to replicate our findings.

KW - Anxiety disorders

KW - Co-morbidity

KW - Neuroticism

KW - Unipolar mood disorders

UR - http://www.scopus.com/inward/record.url?scp=77956646788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77956646788&partnerID=8YFLogxK

U2 - 10.1017/S0033291709991449

DO - 10.1017/S0033291709991449

M3 - Article

VL - 40

SP - 1125

EP - 1136

JO - Psychological Medicine

JF - Psychological Medicine

SN - 0033-2917

IS - 7

ER -