New Challenges in Detecting, Grading, and Staging Endometrial Cancer After Uterine Morcellation

Colleen Rivard*, Alia Salhadar, Kimberly Kenton

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Study Objective: To evaluate the accuracy in diagnosing endometrial disease after uterine morcellation. Design: Prospective case series. Setting: University medical center. Patients: Five women undergoing hysterectomy without morcellation because of benign indications and 5 women with endometrial cancer. Interventions: Uterine specimens were obtained from all 10 study patients. The uteri were sent for pathologic analysis, processed, and fixed according to standard protocols. A single investigator then morcellated all 10 uteri. A single pathologist blinded to specimen group reviewed each specimen. Main Results: The pathologist identified endometrial cancer in 4 of 5 specimens of known cancer. The fifth specimen was interpreted as benign despite the presence of grade 1, stage IA endometrial adenocarcinoma. None of the morcellated specimens could be staged. Conclusion: The increasing use of uterine morcellation will result in new challenges for gynecologic oncologists secondary to difficulty in detection, and accurate grading and staging of endometrial cancer.

Original languageEnglish (US)
Pages (from-to)313-316
Number of pages4
JournalJournal of Minimally Invasive Gynecology
Volume19
Issue number3
DOIs
StatePublished - May 1 2012

Keywords

  • Cancer staging
  • Uterine cancer
  • Uterine morcellation

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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