TY - JOUR
T1 - New concepts in the pathogenesis of urinary tract infections
AU - Schaeffer, Anthony J.
PY - 2002/7/17
Y1 - 2002/7/17
N2 - Random amplified polymorphic DNA fingerprinting was used to distinguish among Escherichia coli bacterial strains creating urinary tract infections (UTIs) in women. Bacteria bound more avidly to cells from postmenopausal donors with history of UTIs (PK) compared with cells from women without history of UTIs (AO). Nonpiliated bacterial strains did not adhere to the cell lines. Increasing S-IgA concentrations has no effect on AO cell bacterial binding, whereas bacterial adhesion to PK cell epithelium increased with increasing S-IgA concentration.
AB - Random amplified polymorphic DNA fingerprinting was used to distinguish among Escherichia coli bacterial strains creating urinary tract infections (UTIs) in women. Bacteria bound more avidly to cells from postmenopausal donors with history of UTIs (PK) compared with cells from women without history of UTIs (AO). Nonpiliated bacterial strains did not adhere to the cell lines. Increasing S-IgA concentrations has no effect on AO cell bacterial binding, whereas bacterial adhesion to PK cell epithelium increased with increasing S-IgA concentration.
UR - http://www.scopus.com/inward/record.url?scp=0036308850&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036308850&partnerID=8YFLogxK
U2 - 10.1016/S0094-0143(02)00010-1
DO - 10.1016/S0094-0143(02)00010-1
M3 - Article
C2 - 12109352
AN - SCOPUS:0036308850
SN - 0094-0143
VL - 29
SP - 241
EP - 250
JO - Urologic Clinics of North America
JF - Urologic Clinics of North America
IS - 1
ER -