New developments in immunotherapies for food allergy

Krishan Dilip Chhiba, Anne Marie Singh, Paul J. Bryce*

*Corresponding author for this work

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

Food allergy affects around 10% of the population. As the prevalence of food allergy continues to increase, disproportionately in children, new therapies for food allergy are being investigated. While there are no approved treatments for food allergy, immunotherapy facilitates significant desensitization and protection from accidental exposure. Nevertheless, current immunotherapies do not entirely nor permanently eliminate sensitivity to the food allergen. Since the rates of sustained unresponsiveness are significantly lower than desensitization, future therapies that enhance the rates of long-term tolerance in patients will catalyze progress in this field over the next 5-10 years.

Original languageEnglish (US)
Pages (from-to)913-922
Number of pages10
JournalImmunotherapy
Volume7
Issue number8
DOIs
StatePublished - Aug 1 2015

Keywords

  • OIT
  • SLIT
  • food allergy
  • immunological tolerance
  • immunotherapy
  • omalizumab
  • oral immunotherapy
  • sublingual immunotherapy

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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    Chhiba, K. D., Singh, A. M., & Bryce, P. J. (2015). New developments in immunotherapies for food allergy. Immunotherapy, 7(8), 913-922. https://doi.org/10.2217/IMT.15.55