New Developments in Interventional Oncology: Liver Metastases from Colorectal Cancer

Joseph R. Kallini, Ahmed Gabr, Nadine Abouchaleh, Rehan Ali, Ahsun Riaz, Robert J. Lewandowski, Riad Salem*

*Corresponding author for this work

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Colorectal cancer is the third leading cause of cancer death in the United States. Although hepatic excision is the first-line treatment for colorectal liver metastasis (CRLM), few patients are candidates. Locoregional therapy (LRT) encompasses minimally invasive techniques practiced by interventional radiology. These include ablative treatments (radiofrequency ablation, microwave ablation, and cryosurgical ablation) and transcatheter intra-arterial therapy (hepatic arterial infusion chemotherapy, transarterial "bland" embolization, transarterial chemoembolization, and radioembolization with yttrium 90). The National Comprehensive Cancer Network recommends LRT for unresectable CRLM refractory to chemotherapy. The following is a review of LRT in CRLM, including salient features, advantages, limitations, current roles, and future considerations.

Original languageEnglish (US)
Pages (from-to)373-380
Number of pages8
JournalCancer Journal (United States)
Volume22
Issue number6
DOIs
StatePublished - Nov 1 2016

Keywords

  • Ablation
  • DEBIRI
  • colorectal liver metastases (CRLM)
  • pump FUDR
  • transarterial chemoembolization (TACE)
  • yttrium 90 (Y)

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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