New discriminatory level for glucosidase activity to diagnose epididymal obstruction or dysfunction

B. Kret, Magdy P Milad*, R. S. Jeyendran

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Neutral αglucosidase activity was measured in seminal plasma of 30 patients consulting for infertility with a variety of disorders, and compared with 25 normal controls. Significantly more of the study populations (asthenozoospermia, 4/6; oligozoospermia, 3/5; azoospermia 8/15) had a neutral αglucosidase activity less than 10 mIU/mL as compared with control samples (3/25). Also the mean (± SD) neutral αglucosidase activity in patients with asthenozoospermia (11.7 ± 9.2) oligozoospermia (11.3 ± 7.2), and post vasectomy azoospermia (5.3 ± 3.4) was significantly (p < 05) less than ejaculate from controls (21.2 ± 14). A seminal αglucosidase level of 10 mlU/mL appears to be a useful discriminatory marker in the diagnosis of epididymal obstruction or dysfunction.

Original languageEnglish (US)
Pages (from-to)29-33
Number of pages5
JournalSystems Biology in Reproductive Medicine
Volume35
Issue number1
DOIs
StatePublished - Jan 1 1995

Keywords

  • Infertility epididymis
  • Male infertility
  • Neutral αglucosidase activity
  • Semen analysis
  • Seminal plasma

ASJC Scopus subject areas

  • Reproductive Medicine
  • Urology

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