New Opportunities and Novel Paradigms to Support Neuromuscular Research

Richard Lieber; Samuel Ward; Lawrence Frank; Simon Schenk

doi:10.1016/j.pmr.2011.11.015

New Opportunities and Novel Paradigms to Support Neuromuscular Research

Richard Lieber^*, Samuel Ward, Lawrence Frank, Simon Schenk

^*Corresponding author for this work

Physical Medicine and Rehabilitation

Research output: Contribution to journal › Review article › peer-review

Abstract

This article provides an overview of the structure and function of the National Skeletal Muscle Research Center (NSMRC) at the University of California, San Diego, which is one of the 7 research centers of the Medical Rehabilitation Research Infrastructure Network, created to facilitate access for physicians to experts, technology, and resources from scientific fields related to medical rehabilitation. The 4 cores of the NSMRC are described as a resource for rehabilitation medicine practitioners to use for clinically relevant muscle research.

Original language	English (US)
Pages (from-to)	95-105
Number of pages	11
Journal	Physical Medicine and Rehabilitation Clinics of North America
Volume	23
Issue number	1
DOIs	https://doi.org/10.1016/j.pmr.2011.11.015
State	Published - Feb 2012

Funding

Rehabilitation clinician-scientists often encounter a variety of primary and secondary diseases that are associated with skeletal muscle. Although muscular dystrophy, sarcopenia, and tendinitis are familiar skeletal muscle problems, diseases with cerebrovascular, coronary artery, and arthritic causes also affect skeletal muscle. Perhaps most importantly, most rehabilitation treatment strategies, regardless of the clinical entity, are directed toward or through skeletal muscle. Currently, scientific investigations in rehabilitation lack state-of-the-art, quantitative tools for measuring acute and chronic skeletal muscle changes. It is unreasonable to expect rehabilitation clinician-scientists to master the myriad of techniques necessary to study skeletal muscle or to put them in proper perspective when choosing methods. To address this methodological and knowledge void, The Medical Rehabilitation Research Infrastructure Network (MRRIN), funded by The National Institute of Child Health and Human Development (NICHD), through the National Center for Medical Rehabilitation Research (NCMRR), the National Institute for Neurologic Disorders and Stroke (NINDS), and the National Institute of Biomedical Imaging and Bioengineering (NIBIB), was created to facilitate access for physicians to experts, technology, and resources from scientific fields related to medical rehabilitation. This work was supported in part by NSMRC R24 HD650837 .

Keywords

Muscle biomechanics
Muscle histology
Muscle imaging
Muscle metabolism
Muscle research
Rehabilitation research

ASJC Scopus subject areas

Rehabilitation
Physical Therapy, Sports Therapy and Rehabilitation

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10.1016/j.pmr.2011.11.015

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title = "New Opportunities and Novel Paradigms to Support Neuromuscular Research",

abstract = "This article provides an overview of the structure and function of the National Skeletal Muscle Research Center (NSMRC) at the University of California, San Diego, which is one of the 7 research centers of the Medical Rehabilitation Research Infrastructure Network, created to facilitate access for physicians to experts, technology, and resources from scientific fields related to medical rehabilitation. The 4 cores of the NSMRC are described as a resource for rehabilitation medicine practitioners to use for clinically relevant muscle research.",

keywords = "Muscle biomechanics, Muscle histology, Muscle imaging, Muscle metabolism, Muscle research, Rehabilitation research",

author = "Richard Lieber and Samuel Ward and Lawrence Frank and Simon Schenk",

note = "Funding Information: Rehabilitation clinician-scientists often encounter a variety of primary and secondary diseases that are associated with skeletal muscle. Although muscular dystrophy, sarcopenia, and tendinitis are familiar skeletal muscle problems, diseases with cerebrovascular, coronary artery, and arthritic causes also affect skeletal muscle. Perhaps most importantly, most rehabilitation treatment strategies, regardless of the clinical entity, are directed toward or through skeletal muscle. Currently, scientific investigations in rehabilitation lack state-of-the-art, quantitative tools for measuring acute and chronic skeletal muscle changes. It is unreasonable to expect rehabilitation clinician-scientists to master the myriad of techniques necessary to study skeletal muscle or to put them in proper perspective when choosing methods. To address this methodological and knowledge void, The Medical Rehabilitation Research Infrastructure Network (MRRIN), funded by The National Institute of Child Health and Human Development (NICHD), through the National Center for Medical Rehabilitation Research (NCMRR), the National Institute for Neurologic Disorders and Stroke (NINDS), and the National Institute of Biomedical Imaging and Bioengineering (NIBIB), was created to facilitate access for physicians to experts, technology, and resources from scientific fields related to medical rehabilitation. Funding Information: This work was supported in part by NSMRC R24 HD650837 . ",

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language = "English (US)",

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New Opportunities and Novel Paradigms to Support Neuromuscular Research

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Keywords

ASJC Scopus subject areas

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