New Technologies for Rapid Bacterial Identification and Antibiotic Resistance Profiling

Shana O. Kelley*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations

Abstract

Conventional approaches to bacterial identification and drug susceptibility testing typically rely on culture-based approaches that take 2 to 7 days to return results. The long turnaround times contribute to the spread of infectious disease, negative patient outcomes, and the misuse of antibiotics that can contribute to antibiotic resistance. To provide new solutions enabling faster bacterial analysis, a variety of approaches are under development that leverage single-cell analysis, microfluidic concentration and detection strategies, and ultrasensitive readout mechanisms. This review discusses recent advances in this area and the potential of new technologies to enable more effective management of infectious disease.

Original languageEnglish (US)
Pages (from-to)113-121
Number of pages9
JournalSLAS Technology
Volume22
Issue number2
DOIs
StatePublished - Apr 1 2017
Externally publishedYes

Keywords

  • clinical automation
  • lab-on-a-chip
  • microfluidics
  • microtechnology

ASJC Scopus subject areas

  • Computer Science Applications
  • Medical Laboratory Technology

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