New Tools in Experimental Cellular Therapy for the Treatment of Liver Diseases

Jennifer R. Ferrer, Attasit Chokechanachaisakul, Jason A. Wertheim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The current standard of care for end stage liver disease is orthotopic liver transplantation (OLT). Through improvement in surgical techniques, immunosuppression, and general medical care, liver transplantation has become an effective treatment over the course of the last half-century. Unfortunately, due to the limited availability of donor organs, there is a finite limit to the number of patients who will benefit from this therapy. This review will discuss current research in experimental cellular therapies for acute, chronic, and metabolic liver failure that may be appropriate when liver transplantation is not an immediate option.

Original languageEnglish (US)
Pages (from-to)202-210
Number of pages9
JournalCurrent Transplantation Reports
Volume2
Issue number2
DOIs
StatePublished - Jun 1 2015

Keywords

  • Alternative cell sources
  • Cellular therapy
  • Hepatocyte transplantation
  • Stem cells

ASJC Scopus subject areas

  • Transplantation
  • Surgery
  • Hepatology
  • Nephrology
  • Immunology

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