Abstract
The article discusses the potential use of gold nanoparticles in next-generation biosensing techniques. Gold nanoparticle probes offer significant advantages over molecular-fluorophore probes in terms of selectivity and sensitivity in DNA detection. From a technological perspective, the sharp melting transitions exhibited by DNA-nanoparticle conjugates are extremely important because the sharpness of the DNA-melting transition effectively determines the selectivity of any hybridization-based assay.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 48-51 |
| Number of pages | 4 |
| Journal | Biophotonics International |
| Volume | 10 |
| Issue number | 6 |
| State | Published - Jul 2003 |
ASJC Scopus subject areas
- Biotechnology