NIH toolbox cognition battery (CB): Validation of executive function measures in adults

Philip David Zelazo*, Jacob E. Anderson, Jennifer Richler, Kathleen Wallner-Allen, Jennifer L. Beaumont, Kevin P. Conway, Richard Gershon, Sandra Weintraub

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

72 Scopus citations

Abstract

This study describes psychometric properties of the NIH Toolbox Cognition Battery (NIHTB-CB) executive function measures in an adult sample. The NIHTB-CB was designed for use in epidemiologic studies and clinical trials for ages 3 to 85. A total of 268 self-described healthy adults were recruited at four university-based sites, using stratified sampling guidelines to target demographic variability for age (20-85 years), gender, education and ethnicity. The NIHTB-CB contains two computer-based instruments assessing executive function: the Dimensional Change Card Sort (a measure of cognitive flexibility) and a flanker task (a measure of inhibitory control and selective attention). Participants completed the NIHTB-CB, corresponding gold standard convergent and discriminant measures, and sociodemographic questionnaires. A subset of participants (N=89) was retested 7 to 21 days later. Results reveal excellent sensitivity to age-related changes during adulthood, excellent test-retest reliability, and adequate to good convergent and discriminant validity. The NIH Toolbox EF measures can be used effectively in epidemiologic and clinical studies.

Original languageEnglish (US)
Pages (from-to)620-629
Number of pages10
JournalJournal of the International Neuropsychological Society
Volume20
Issue number6
DOIs
StatePublished - Jul 2014

Keywords

  • Cognitive control
  • Cognitive flexibility
  • Inhibitory control
  • Lifespan development
  • Standardized testing
  • Validation

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

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