Nocturnal activity with nighttime pergolide in Parkinson disease: A controlled study using actigraphy

Cynthia L. Comella; Mary Morrissey; Kimberly Janko

doi:10.1212/01.WNL.0000158652.74601.48

Nocturnal activity with nighttime pergolide in Parkinson disease: A controlled study using actigraphy

Cynthia L. Comella^*, Mary Morrissey, Kimberly Janko

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Pergolide is a dopamine agonist that improves Parkinson disease but is associated with dose-dependent sleepiness. This study evaluates the effect of a nighttime dose of 1 mg of pergolide on actigraphic measures of sleep using a randomized, double-blind, placebo-controlled study design. The pergolide group (n = 10) worsened in actigraphic measures of sleep efficiency and sleep fragmentation vs the placebo group (n = 12). Side effects were more frequent in the pergolide group.

Original language	English (US)
Pages (from-to)	1450-1451
Number of pages	2
Journal	Neurology
Volume	64
Issue number	8
DOIs	https://doi.org/10.1212/01.WNL.0000158652.74601.48
State	Published - Apr 26 2005

ASJC Scopus subject areas

Clinical Neurology

Access to Document

10.1212/01.WNL.0000158652.74601.48

Cite this

@article{fbf45b6e16b24983be9b8584344f32e3,

title = "Nocturnal activity with nighttime pergolide in Parkinson disease: A controlled study using actigraphy",

abstract = "Pergolide is a dopamine agonist that improves Parkinson disease but is associated with dose-dependent sleepiness. This study evaluates the effect of a nighttime dose of 1 mg of pergolide on actigraphic measures of sleep using a randomized, double-blind, placebo-controlled study design. The pergolide group (n = 10) worsened in actigraphic measures of sleep efficiency and sleep fragmentation vs the placebo group (n = 12). Side effects were more frequent in the pergolide group.",

author = "Comella, {Cynthia L.} and Mary Morrissey and Kimberly Janko",

year = "2005",

month = apr,

day = "26",

doi = "10.1212/01.WNL.0000158652.74601.48",

language = "English (US)",

volume = "64",

pages = "1450--1451",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

number = "8",

}

TY - JOUR

T1 - Nocturnal activity with nighttime pergolide in Parkinson disease

T2 - A controlled study using actigraphy

AU - Comella, Cynthia L.

AU - Morrissey, Mary

AU - Janko, Kimberly

PY - 2005/4/26

Y1 - 2005/4/26

N2 - Pergolide is a dopamine agonist that improves Parkinson disease but is associated with dose-dependent sleepiness. This study evaluates the effect of a nighttime dose of 1 mg of pergolide on actigraphic measures of sleep using a randomized, double-blind, placebo-controlled study design. The pergolide group (n = 10) worsened in actigraphic measures of sleep efficiency and sleep fragmentation vs the placebo group (n = 12). Side effects were more frequent in the pergolide group.

AB - Pergolide is a dopamine agonist that improves Parkinson disease but is associated with dose-dependent sleepiness. This study evaluates the effect of a nighttime dose of 1 mg of pergolide on actigraphic measures of sleep using a randomized, double-blind, placebo-controlled study design. The pergolide group (n = 10) worsened in actigraphic measures of sleep efficiency and sleep fragmentation vs the placebo group (n = 12). Side effects were more frequent in the pergolide group.

UR - http://www.scopus.com/inward/record.url?scp=17644376221&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17644376221&partnerID=8YFLogxK

U2 - 10.1212/01.WNL.0000158652.74601.48

DO - 10.1212/01.WNL.0000158652.74601.48

M3 - Article

C2 - 15851743

AN - SCOPUS:17644376221

SN - 0028-3878

VL - 64

SP - 1450

EP - 1451

JO - Neurology

JF - Neurology

IS - 8

ER -

Nocturnal activity with nighttime pergolide in Parkinson disease: A controlled study using actigraphy

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this