Non-Alcoholic Fatty Liver Disease: Is Bariatric Surgery the Answer?

Anjana A. Pillai; Mary E. Rinella

doi:10.1016/j.cld.2009.07.012

Non-Alcoholic Fatty Liver Disease: Is Bariatric Surgery the Answer?

Anjana A. Pillai, Mary E. Rinella^*

^*Corresponding author for this work

Medicine, Hepatology Division

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

As the worldwide obesity epidemic continues to increase, the prevalence of non-alcoholic fatty liver disease (NAFLD) and specifically non-alcoholic steatohepatitis (NASH) will become increasingly prominent. NASH will surpass chronic hepatitis C infection as the primary indication for orthotopic liver transplantation in the near future. With the evolution of surgical techniques, bariatric surgery is currently recognized as the most effective method for achieving sustained weight loss and reversing numerous comorbidities in severely obese individuals. This review focuses on the potential risks and benefits of bariatric surgery in subjects with NAFLD and explores its role in the management of NASH in the obese patient.

Original language	English (US)
Pages (from-to)	689-710
Number of pages	22
Journal	Clinics in liver disease
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.cld.2009.07.012
State	Published - Nov 2009

Keywords

Bariatric surgery
Gastric banding
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Roux-en-Y gastric bypass

ASJC Scopus subject areas

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cld.2009.07.012

Cite this

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title = "Non-Alcoholic Fatty Liver Disease: Is Bariatric Surgery the Answer?",

abstract = "As the worldwide obesity epidemic continues to increase, the prevalence of non-alcoholic fatty liver disease (NAFLD) and specifically non-alcoholic steatohepatitis (NASH) will become increasingly prominent. NASH will surpass chronic hepatitis C infection as the primary indication for orthotopic liver transplantation in the near future. With the evolution of surgical techniques, bariatric surgery is currently recognized as the most effective method for achieving sustained weight loss and reversing numerous comorbidities in severely obese individuals. This review focuses on the potential risks and benefits of bariatric surgery in subjects with NAFLD and explores its role in the management of NASH in the obese patient.",

keywords = "Bariatric surgery, Gastric banding, Non-alcoholic fatty liver disease, Non-alcoholic steatohepatitis, Roux-en-Y gastric bypass",

author = "Pillai, {Anjana A.} and Rinella, {Mary E.}",

year = "2009",

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pages = "689--710",

journal = "Clinics in Liver Disease",

issn = "1089-3261",

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T1 - Non-Alcoholic Fatty Liver Disease

T2 - Is Bariatric Surgery the Answer?

AU - Pillai, Anjana A.

AU - Rinella, Mary E.

PY - 2009/11

Y1 - 2009/11

N2 - As the worldwide obesity epidemic continues to increase, the prevalence of non-alcoholic fatty liver disease (NAFLD) and specifically non-alcoholic steatohepatitis (NASH) will become increasingly prominent. NASH will surpass chronic hepatitis C infection as the primary indication for orthotopic liver transplantation in the near future. With the evolution of surgical techniques, bariatric surgery is currently recognized as the most effective method for achieving sustained weight loss and reversing numerous comorbidities in severely obese individuals. This review focuses on the potential risks and benefits of bariatric surgery in subjects with NAFLD and explores its role in the management of NASH in the obese patient.

AB - As the worldwide obesity epidemic continues to increase, the prevalence of non-alcoholic fatty liver disease (NAFLD) and specifically non-alcoholic steatohepatitis (NASH) will become increasingly prominent. NASH will surpass chronic hepatitis C infection as the primary indication for orthotopic liver transplantation in the near future. With the evolution of surgical techniques, bariatric surgery is currently recognized as the most effective method for achieving sustained weight loss and reversing numerous comorbidities in severely obese individuals. This review focuses on the potential risks and benefits of bariatric surgery in subjects with NAFLD and explores its role in the management of NASH in the obese patient.

KW - Bariatric surgery

KW - Gastric banding

KW - Non-alcoholic fatty liver disease

KW - Non-alcoholic steatohepatitis

KW - Roux-en-Y gastric bypass

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Non-Alcoholic Fatty Liver Disease: Is Bariatric Surgery the Answer?

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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