Non-blinking "Giant" nanocrystal quantum dots: Ideal probes for real-time three-dimensional tracking

Jennifer A. Hollingsworth*, James H. Werner, Han Htoon, Andrei Piryatinski, Richard Schaller, Yagnaseni Ghosh, Allison M. Dennis, Aaron M. Keller, Benjamin Mangum, Daniel C. Hannah

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We describe the development and characterization of two novel non-blinking "giant" nanocrystal quantum dot (g-NQD) systems and their application to single-particle tracking in live cells real-time and in three dimensions. The two g-NQDs - CdSe/CdS and InP/CdS - are characterized by a thick shell layer (>10 monolayers of CdS), a quasi-type-II or type-II electronic structure, and extremely suppressed non-radiative Auger recombination and photobleaching, in addition to suppressed blinking. We show that these unique traits make this new class of NQD ideal molecular probes for observing spatio-temporal dynamics of cellular processes.

Original languageEnglish (US)
Title of host publicationCLEO
Subtitle of host publicationQELS_Fundamental Science, CLEO:QELS FS 2013
PagesQTu1P.3
StatePublished - 2013
EventCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013 - San Jose, CA, United States
Duration: Jun 9 2013Jun 14 2013

Publication series

NameCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013

Other

OtherCLEO: QELS_Fundamental Science, CLEO:QELS FS 2013
Country/TerritoryUnited States
CitySan Jose, CA
Period6/9/136/14/13

ASJC Scopus subject areas

  • Computer Networks and Communications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics

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