Abstract
CNS non-cerebellar primitive neuroectodermal tumors (PNET) represent <5% of all childhood brain tumors. Despite similar therapies, these patients have had significantly worse outcomes compared to patients with medulloblastoma. Although these tumors have historically been considered analogous to medulloblastoma, there is growing evidence that they are biologically distinct. Since these tumors are relatively rare, there are few large series in the literature. Here we present the international experience treating these patients with a variety of therapies, including marrow ablative chemotherapy followed by autologous hematopoietic cell rescue.
Original language | English (US) |
---|---|
Pages (from-to) | 638-640 |
Number of pages | 3 |
Journal | Pediatric Blood and Cancer |
Volume | 54 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2010 |
Keywords
- Autologous transplant
- Brain tumors
- PNET
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology