TY - GEN
T1 - Non-invasive assessment of cardiac contractility on a weighing scale
AU - Etemadi, Mozziyar
AU - Inan, Omer T.
AU - Wiard, Richard M.
AU - Kovacs, Gregory T A
AU - Giovangrandi, Laurent
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Myocardial contractility, the intrinsic ability of the heart muscle to produce force, has been difficult to quantify non-invasively. Pre-ejection-period (PEP), the time the ventricles spend in isovolumetric contraction, is widely accepted as a way to measure contractility. This work presents a way by which the ballistocardiogram - a readily accessible noninvasive cardiovascular signal - can be used in tandem with the electrocardiogram to obtain a parameter highly correlated to PEP and thus to myocardial contractility. This parameter is the delay from the electrocardiogram R-wave to the peak (the J-wave) of the ballistocardiogram. In this work, we showed that this delay, the RJ interval, was correlated to PEP (r2 = 0.75) for 709 heartbeats across 4 subjects, with a slope of 1.11, and a y-intercept of 151 ms. This suggests that the RJ interval can be used in place of the PEP for a reliable, practical, and noninvasive assessment of myocardial contractility.
AB - Myocardial contractility, the intrinsic ability of the heart muscle to produce force, has been difficult to quantify non-invasively. Pre-ejection-period (PEP), the time the ventricles spend in isovolumetric contraction, is widely accepted as a way to measure contractility. This work presents a way by which the ballistocardiogram - a readily accessible noninvasive cardiovascular signal - can be used in tandem with the electrocardiogram to obtain a parameter highly correlated to PEP and thus to myocardial contractility. This parameter is the delay from the electrocardiogram R-wave to the peak (the J-wave) of the ballistocardiogram. In this work, we showed that this delay, the RJ interval, was correlated to PEP (r2 = 0.75) for 709 heartbeats across 4 subjects, with a slope of 1.11, and a y-intercept of 151 ms. This suggests that the RJ interval can be used in place of the PEP for a reliable, practical, and noninvasive assessment of myocardial contractility.
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U2 - 10.1109/IEMBS.2009.5332508
DO - 10.1109/IEMBS.2009.5332508
M3 - Conference contribution
C2 - 19963690
AN - SCOPUS:77951005618
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 6773
EP - 6776
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -