Noncoding RNAs, Neurodevelopment, and Neurodegeneration

Mengmeng Chen; Jianwen Deng; Mengxue Yang; Kun Zhu; Jianghong Liu; Li Zhu; Jane Y. Wu

doi:10.1002/9783527665433.ch9

Noncoding RNAs, Neurodevelopment, and Neurodegeneration

Mengmeng Chen^*, Jianwen Deng, Mengxue Yang, Kun Zhu, Jianghong Liu, Li Zhu, Jane Y. Wu

^*Corresponding author for this work

Neurology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

Noncoding RNA (ncRNA) genes are emerging as versatile regulators of gene expression and function. However, our knowledge about ncRNAs remains limited. Here, we review recent studies on the role of ncRNAs in neurodevelopment and neurodegeneration. A global picture of the complex networks regulating and regulated by ncRNAs is just beginning to emerge. Great challenges remain in understanding the biological function of thousands of ncRNAs and their involvement in the pathogenesis of human diseases.

Original language	English (US)
Title of host publication	Post-Transcriptional Gene Regulation
Subtitle of host publication	RNA Processing in Eukaryotes
Publisher	Wiley-Blackwell
Pages	215-238
Number of pages	24
ISBN (Electronic)	9783527665433
ISBN (Print)	9783527322022
DOIs	https://doi.org/10.1002/9783527665433.ch9
State	Published - Jan 1 2013

Keywords

NcRNA
Neurodegenerative
Neurodevelopment
Posttranscriptional gene regulation

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/9783527665433.ch9

Cite this

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abstract = "Noncoding RNA (ncRNA) genes are emerging as versatile regulators of gene expression and function. However, our knowledge about ncRNAs remains limited. Here, we review recent studies on the role of ncRNAs in neurodevelopment and neurodegeneration. A global picture of the complex networks regulating and regulated by ncRNAs is just beginning to emerge. Great challenges remain in understanding the biological function of thousands of ncRNAs and their involvement in the pathogenesis of human diseases.",

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T1 - Noncoding RNAs, Neurodevelopment, and Neurodegeneration

AU - Chen, Mengmeng

AU - Deng, Jianwen

AU - Yang, Mengxue

AU - Zhu, Kun

AU - Liu, Jianghong

AU - Zhu, Li

AU - Wu, Jane Y.

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Noncoding RNA (ncRNA) genes are emerging as versatile regulators of gene expression and function. However, our knowledge about ncRNAs remains limited. Here, we review recent studies on the role of ncRNAs in neurodevelopment and neurodegeneration. A global picture of the complex networks regulating and regulated by ncRNAs is just beginning to emerge. Great challenges remain in understanding the biological function of thousands of ncRNAs and their involvement in the pathogenesis of human diseases.

AB - Noncoding RNA (ncRNA) genes are emerging as versatile regulators of gene expression and function. However, our knowledge about ncRNAs remains limited. Here, we review recent studies on the role of ncRNAs in neurodevelopment and neurodegeneration. A global picture of the complex networks regulating and regulated by ncRNAs is just beginning to emerge. Great challenges remain in understanding the biological function of thousands of ncRNAs and their involvement in the pathogenesis of human diseases.

KW - NcRNA

KW - Neurodegenerative

KW - Neurodevelopment

KW - Posttranscriptional gene regulation

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M3 - Chapter

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EP - 238

BT - Post-Transcriptional Gene Regulation

PB - Wiley-Blackwell

ER -

Noncoding RNAs, Neurodevelopment, and Neurodegeneration

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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