Noncoding RNAs, Neurodevelopment, and Neurodegeneration

Mengmeng Chen*, Jianwen Deng, Mengxue Yang, Kun Zhu, Jianghong Liu, Li Zhu, Jane Y. Wu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Noncoding RNA (ncRNA) genes are emerging as versatile regulators of gene expression and function. However, our knowledge about ncRNAs remains limited. Here, we review recent studies on the role of ncRNAs in neurodevelopment and neurodegeneration. A global picture of the complex networks regulating and regulated by ncRNAs is just beginning to emerge. Great challenges remain in understanding the biological function of thousands of ncRNAs and their involvement in the pathogenesis of human diseases.

Original languageEnglish (US)
Title of host publicationPost-Transcriptional Gene Regulation
Subtitle of host publicationRNA Processing in Eukaryotes
PublisherWiley Blackwell
Pages215-238
Number of pages24
ISBN (Electronic)9783527665433
ISBN (Print)9783527322022
DOIs
StatePublished - Jan 1 2013

Keywords

  • NcRNA
  • Neurodegenerative
  • Neurodevelopment
  • Posttranscriptional gene regulation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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