Noninvasive CT diagnosis of infantile Alexander disease: Pathologic correlation

Barbara L. Trommer, Thomas P. Naidich*, Mauro Carlo Dal Canto, David G McLone, Marianne B. Larsen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Noninvasive computed tomography provided the initial, accurate diagnosis of a necropsy-proven case of infantile Alexander disease, demonstrated serial changes in the intensity and distribution of leukodystrophy, and documented a progressive alteration of brain density from abnormally high attenuation to abnormally low attenuation as the disease advanced.

Original languageEnglish (US)
Pages (from-to)509-516
Number of pages8
JournalJournal of Computer Assisted Tomography
Issue number3
StatePublished - Jan 1 1983


  • Alexander disease
  • Brain, disease
  • Computed tomography
  • Infants
  • Leukodystrophy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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