Noninvasive diagnosis of infection using plasma next-generation sequencing: A single-center experience

Jenna Rossoff, Sonali Chaudhury, Maulin Soneji, Sameer J. Patel, Soyang Kwon, Amy Armstrong, William J. Muller*

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Pediatric patients frequently present with illnesses strongly suggesting infection, but without a clearly identified etiology. Our center has recently added a commercially available plasma metagenomic sequencing assay to its available diagnostic testing. Our experience with the first 100 tests suggests that this technology has good clinical performance with >90% sensitivity.

Original languageEnglish (US)
Article numberofz327
JournalOpen Forum Infectious Diseases
Volume6
Issue number8
DOIs
StatePublished - Jun 3 2019

Keywords

  • bacterial infection
  • metagenomic next-generation sequencing
  • viral infection

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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