Noninvasive in vivo imaging of oxygen metabolic rate in the retina

Wenzhong Liu, Hao F. Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

Precise and noninvasive measurement of retinal oxygen metabolic rate is important for retinal pathological investigations as well as retinal disease detection, which has not been achieved until recently. Here, we quantified retinal oxygen metabolic rate in rats by combining photoacoustic ophthalmoscopy with spectral domain-optical coherence tomography. We employed multi-wavelength photoacoustic ophthalmoscopy for oxygen saturation measurement and applied dual-ring scanning Doppler spectral domain-optical coherence tomography to image retinal blood flow. With retinal oxygen saturation and blood flow being measured, we determined the retinal oxygen metabolic rate in a typical rat to be 373.41 ± 88.04 ng/minute.

Original languageEnglish (US)
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages3865-3868
Number of pages4
ISBN (Electronic)9781424479290
DOIs
StatePublished - Nov 2 2014
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: Aug 26 2014Aug 30 2014

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period8/26/148/30/14

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

Fingerprint Dive into the research topics of 'Noninvasive in vivo imaging of oxygen metabolic rate in the retina'. Together they form a unique fingerprint.

Cite this