TY - JOUR
T1 - Nonoliguric Acute Renal Failure After Captopril Therapy
AU - Fotino, Serban
AU - Sporn, Peter
PY - 1983/1/1
Y1 - 1983/1/1
N2 - In a patient with severe renovascular hypertension, nonoliguric acute renal failure developed after she received captopril treatment. We believe this to be a previously unreported complication. Urine volume ranged from 1,640 to 2,260 mL/24 hr, and serum creatinine level rose from 2.3 to 8.3 mg/dL. There was no evidence of renal hypoperfusion or interstitial nephritis. Acute renal failure most likely was secondary to the nephrotoxic effect of captopril on chronically hypoperfused kidneys. Renal function improved rapidly after withdrawal of the drug therapy.
AB - In a patient with severe renovascular hypertension, nonoliguric acute renal failure developed after she received captopril treatment. We believe this to be a previously unreported complication. Urine volume ranged from 1,640 to 2,260 mL/24 hr, and serum creatinine level rose from 2.3 to 8.3 mg/dL. There was no evidence of renal hypoperfusion or interstitial nephritis. Acute renal failure most likely was secondary to the nephrotoxic effect of captopril on chronically hypoperfused kidneys. Renal function improved rapidly after withdrawal of the drug therapy.
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U2 - 10.1001/archinte.1983.00350060184031
DO - 10.1001/archinte.1983.00350060184031
M3 - Article
C2 - 6344831
AN - SCOPUS:0020628287
VL - 143
SP - 1252
EP - 1253
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 6
ER -