Nonresectional regional therapies for metastatic colorectal cancer to the liver

Cary Jo R. Schlick, Ryan Patrick Merkow, David Jason Bentrem*

*Corresponding author for this work

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

The liver is the second leading site of colorectal cancer metastases, following the lymph nodes. Although metastatic resection for colorectal cancer liver metastases has been shown to improve survival, many patients cannot undergo surgery. Several nonsurgical therapies are available in these situations, however high-quality evidence comparing the effectiveness of these therapies is sparse. Here, we review the currently available evidence in support of nonresectional regional therapies for colorectal metastases to the liver.

Original languageEnglish (US)
JournalJournal of Surgical Oncology
DOIs
StatePublished - Jan 1 2019

Fingerprint

Liver Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Liver
Therapeutics
Lymph Nodes
Survival

Keywords

  • colorectal cancer
  • hepatic metastases
  • liver-directed therapy
  • metastatic colorectal cancer
  • regional therapies

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

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title = "Nonresectional regional therapies for metastatic colorectal cancer to the liver",
abstract = "The liver is the second leading site of colorectal cancer metastases, following the lymph nodes. Although metastatic resection for colorectal cancer liver metastases has been shown to improve survival, many patients cannot undergo surgery. Several nonsurgical therapies are available in these situations, however high-quality evidence comparing the effectiveness of these therapies is sparse. Here, we review the currently available evidence in support of nonresectional regional therapies for colorectal metastases to the liver.",
keywords = "colorectal cancer, hepatic metastases, liver-directed therapy, metastatic colorectal cancer, regional therapies",
author = "Schlick, {Cary Jo R.} and Merkow, {Ryan Patrick} and Bentrem, {David Jason}",
year = "2019",
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language = "English (US)",
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AU - Schlick, Cary Jo R.

AU - Merkow, Ryan Patrick

AU - Bentrem, David Jason

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Y1 - 2019/1/1

N2 - The liver is the second leading site of colorectal cancer metastases, following the lymph nodes. Although metastatic resection for colorectal cancer liver metastases has been shown to improve survival, many patients cannot undergo surgery. Several nonsurgical therapies are available in these situations, however high-quality evidence comparing the effectiveness of these therapies is sparse. Here, we review the currently available evidence in support of nonresectional regional therapies for colorectal metastases to the liver.

AB - The liver is the second leading site of colorectal cancer metastases, following the lymph nodes. Although metastatic resection for colorectal cancer liver metastases has been shown to improve survival, many patients cannot undergo surgery. Several nonsurgical therapies are available in these situations, however high-quality evidence comparing the effectiveness of these therapies is sparse. Here, we review the currently available evidence in support of nonresectional regional therapies for colorectal metastases to the liver.

KW - colorectal cancer

KW - hepatic metastases

KW - liver-directed therapy

KW - metastatic colorectal cancer

KW - regional therapies

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