Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy

Anne Grosen; Emanuelle Bellaguarda; Ingela Liljeqvist-Soltic; Mette Mejlby Hansen; Anne Bine Skytte; Mette Julsgaard; Stephen B. Hanauer; Jens Kelsen

doi:10.1093/ibd/izac028

Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy

Anne Grosen^*, Emanuelle Bellaguarda, Ingela Liljeqvist-Soltic, Mette Mejlby Hansen, Anne Bine Skytte, Mette Julsgaard, Stephen B. Hanauer, Jens Kelsen

^*Corresponding author for this work

Medicine, Gastroenterology Division

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.

Original language	English (US)
Pages (from-to)	1603-1606
Number of pages	4
Journal	Inflammatory bowel diseases
Volume	28
Issue number	10
DOIs	https://doi.org/10.1093/ibd/izac028
State	Published - Oct 1 2022

Keywords

inflammatory bowel disease
sperm DNA integrity
ustekinumab

ASJC Scopus subject areas

Gastroenterology
Immunology and Allergy

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10.1093/ibd/izac028

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abstract = "We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.",

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author = "Anne Grosen and Emanuelle Bellaguarda and Ingela Liljeqvist-Soltic and {Mejlby Hansen}, Mette and Skytte, {Anne Bine} and Mette Julsgaard and Hanauer, {Stephen B.} and Jens Kelsen",

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AU - Grosen, Anne

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AU - Mejlby Hansen, Mette

AU - Skytte, Anne Bine

AU - Julsgaard, Mette

AU - Hanauer, Stephen B.

AU - Kelsen, Jens

PY - 2022/10/1

Y1 - 2022/10/1

N2 - We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.

AB - We demonstrate that ustekinumab does not adversely affect semen quality or sex hormones in male patients. Ustekinumab is not detectable in semen and poses no risk to partners. Our observations support a recommendation to continue ustekinumab therapy in patients wishing to conceive.

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KW - sperm DNA integrity

KW - ustekinumab

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Normal Sperm DNA Integrity in Patients With Inflammatory Bowel Disease on Ustekinumab Maintenance Therapy

Abstract

Keywords

ASJC Scopus subject areas

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