Nosocomial colonization and infection in persons infected with human immunodeficiency virus.

D. E. Craven*, K. A. Steger, L. R. Hirschhorn

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Nosocomial infections appear to be increased in patients with acquired immunodeficiency syndrome (AIDS), compared to individuals with asymptomatic infection due to human immunodeficiency virus (HIV). Risk factors for bacterial colonization and infection include immunosuppression, prior treatment with some antibiotics, increased hospitalizations with longer lengths of stay, greater exposure to invasive devices such as indwelling intravenous or urinary catheters, and the degree of immunosuppression. Data suggest that other infectious agents such as Pneumocystis carinii, Mycobacterium tuberculosis, Mycobacterium avium complex, and Cryptosporidium may be acquired in healthcare facilities. Diagnosis and management of nosocomial infections in HIV-infected persons may be complicated by an atypical presentation, increased rates of relapse following treatment, presence of multiple infections, and early discharge from the inpatient setting. Accurate assessment of nosocomial infections and outbreaks in the hospital is complicated by limited data on the risk of transmission of both traditional and unusual pathogens in this population. Furthermore, some patients may acquire nosocomial pathogens during their initial hospitalization and present later with infections that normally would be classified as community acquired. Therefore, there probably is an underestimation of current nosocomial infection rates, and perhaps "hospital-associated" or "healthcare-facility-associated" might be more accurate terms for these infections.

Original languageEnglish (US)
Pages (from-to)304-318
Number of pages15
JournalInfection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America
Issue number5
StatePublished - May 1996

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Nosocomial colonization and infection in persons infected with human immunodeficiency virus.'. Together they form a unique fingerprint.

Cite this