Notch signaling: A rheostat regulating oligodendrocyte differentiation?

Brian Popko*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Recent studies suggest that Notch signaling provides both instructive and inhibitory cues for oligodendroglial differentiation, depending on the developmental stage and the stimulatory ligand. In the October 17 issue of Cell, Hu et al. present the axonal cell adhesion molecule contactin as a functional Notch ligand, and suggest interesting potential roles for axoglial interactions in regulating oligodendroglial maturation.

Original languageEnglish (US)
Pages (from-to)668-669
Number of pages2
JournalDevelopmental Cell
Issue number5
StatePublished - Nov 2003

ASJC Scopus subject areas

  • Molecular Biology
  • General Biochemistry, Genetics and Molecular Biology
  • Developmental Biology
  • Cell Biology


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