Abstract
Protecting group chemistry on derivatives of T-2 toxin (2) involving silylation (TBDMS ethers) of the hydroxyl groups at C-3 and C-4, and acetalation (benzylidene acetals) of the C-8 and C-15 hydroxyl groups, has afforded the 3,4- and 8,15-polyether analogues 9-12 and 18 and 19 of macrocyclic trichothecenes.
Original language | English (US) |
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Pages (from-to) | 2657-2660 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 28 |
Issue number | 23 |
DOIs | |
State | Published - 1987 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry