Novel methods for assessment of right heart structure and function in pulmonary hypertension

Gautam K. Singh; Philip T. Levy; Mark R. Holland; Aaron Hamvas

doi:10.1016/j.clp.2012.06.002

Novel methods for assessment of right heart structure and function in pulmonary hypertension

Gautam K. Singh^*, Philip T. Levy, Mark R. Holland, Aaron Hamvas

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Long-term increases in pulmonary vascular resistance and pulmonary arterial pressure resulting from structural alterations and abnormal vasoreactivity of the pulmonary vasculature may lead to right ventricular (RV) remodeling. Conventional methods of assessment of RV structure and function do not provide sensitive markers of RV remodeling for prognostic information. Advances in cardiac imaging have provided the capability to obtain quantitative information on the RV structure and function. This article reviews the clinical conditions that result in PH and discusses the novel and emerging methods for the assessment of right heart structure and function in PH in infants and children.

Original language	English (US)
Pages (from-to)	685-701
Number of pages	17
Journal	Clinics in Perinatology
Volume	39
Issue number	3
DOIs	https://doi.org/10.1016/j.clp.2012.06.002
State	Published - Sep 2012

Keywords

Echocardiography
Heart function
Magnetic resonance imaging
Pulmonary hypertension
Right ventricle

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1016/j.clp.2012.06.002

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title = "Novel methods for assessment of right heart structure and function in pulmonary hypertension",

abstract = "Long-term increases in pulmonary vascular resistance and pulmonary arterial pressure resulting from structural alterations and abnormal vasoreactivity of the pulmonary vasculature may lead to right ventricular (RV) remodeling. Conventional methods of assessment of RV structure and function do not provide sensitive markers of RV remodeling for prognostic information. Advances in cardiac imaging have provided the capability to obtain quantitative information on the RV structure and function. This article reviews the clinical conditions that result in PH and discusses the novel and emerging methods for the assessment of right heart structure and function in PH in infants and children.",

keywords = "Echocardiography, Heart function, Magnetic resonance imaging, Pulmonary hypertension, Right ventricle",

author = "Singh, {Gautam K.} and Levy, {Philip T.} and Holland, {Mark R.} and Aaron Hamvas",

year = "2012",

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doi = "10.1016/j.clp.2012.06.002",

language = "English (US)",

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TY - JOUR

T1 - Novel methods for assessment of right heart structure and function in pulmonary hypertension

AU - Singh, Gautam K.

AU - Levy, Philip T.

AU - Holland, Mark R.

AU - Hamvas, Aaron

PY - 2012/9

Y1 - 2012/9

N2 - Long-term increases in pulmonary vascular resistance and pulmonary arterial pressure resulting from structural alterations and abnormal vasoreactivity of the pulmonary vasculature may lead to right ventricular (RV) remodeling. Conventional methods of assessment of RV structure and function do not provide sensitive markers of RV remodeling for prognostic information. Advances in cardiac imaging have provided the capability to obtain quantitative information on the RV structure and function. This article reviews the clinical conditions that result in PH and discusses the novel and emerging methods for the assessment of right heart structure and function in PH in infants and children.

AB - Long-term increases in pulmonary vascular resistance and pulmonary arterial pressure resulting from structural alterations and abnormal vasoreactivity of the pulmonary vasculature may lead to right ventricular (RV) remodeling. Conventional methods of assessment of RV structure and function do not provide sensitive markers of RV remodeling for prognostic information. Advances in cardiac imaging have provided the capability to obtain quantitative information on the RV structure and function. This article reviews the clinical conditions that result in PH and discusses the novel and emerging methods for the assessment of right heart structure and function in PH in infants and children.

KW - Echocardiography

KW - Heart function

KW - Magnetic resonance imaging

KW - Pulmonary hypertension

KW - Right ventricle

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DO - 10.1016/j.clp.2012.06.002

M3 - Review article

C2 - 22954276

AN - SCOPUS:84865786574

SN - 0095-5108

VL - 39

SP - 685

EP - 701

JO - Clinics in Perinatology

JF - Clinics in Perinatology

IS - 3

ER -

Novel methods for assessment of right heart structure and function in pulmonary hypertension

Abstract

Keywords

ASJC Scopus subject areas

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