Novel signaling pathway through the β-adrenergic receptor

Yong Chao Ma, Xin Yun Huang*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

β -Adrenergic receptors transduce signals through the heterotrimeric G protein Gαs to regulate cardiac function. Recently, it has been discovered that Gαs could directly stimulate the Src family tyrosine kinase activity. This novel signaling pathway provides insights into the cAMP-PKA-independent signaling mechanisms used by β -adrenergic receptors to regulate apoptosis, receptor desensitization, and other physiological functions.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
JournalTrends in Cardiovascular Medicine
Volume12
Issue number1
DOIs
StatePublished - Jan 19 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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