Novel swine-origin (S-OIV) H1N1 influenza a pneumonia in a lung transplant patient: A case report and review of the literature on performance characteristics of rapid screening tests for the S-OIV

Rishi Raj*, Mario Cerdan, Andresfelipe Yepeshurtado, Robert Kimbrough, Kenneth Nugent

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Rapid screening tests are insensitive for detecting the novel swine-origin influenza A (H1N1) virus (S-OIV), and false negatives can delay the diagnosis and initiation of appropriate antiviral therapy. The case of a 26-year-old double lung transplant recipient presenting with fever, bilateral pulmonary infiltrates, and a negative influenza direct immunofluorescent antibody on bronchoalveolar lavage is presented. A diagnosis was made, and antiviral therapy was started 10 days after the initial bronchoalveolar lavage on receipt of a positive culture for S-OIV. The published literature on the performance characteristics of rapid screening tests for S-OIV is reviewed in this clinical context.

Original languageEnglish (US)
Pages (from-to)506-508
Number of pages3
JournalAmerican Journal of the Medical Sciences
Volume338
Issue number6
DOIs
StatePublished - Dec 2009

Keywords

  • Immunosuppressed
  • Novel influenza A
  • Pneumonia
  • Rapid tests
  • Screening

ASJC Scopus subject areas

  • Medicine(all)

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