Nuclear architecture: The cell biology of a laminopathy

Jason H. Brickner

doi:10.1016/j.cub.2011.09.006

Nuclear architecture: The cell biology of a laminopathy

Jason H. Brickner^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

2 Scopus citations

Abstract

Lamin mutations cause muscular dystrophies, but the mechanism is unclear. A new study shows that lamin mutant worms display muscle-specific defects linked to altered subnuclear localization of heterochromatin, leading to altered gene expression.

Original language	English (US)
Pages (from-to)	R807-R809
Journal	Current Biology
Volume	21
Issue number	19
DOIs	https://doi.org/10.1016/j.cub.2011.09.006
State	Published - Oct 11 2011

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2011.09.006

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title = "Nuclear architecture: The cell biology of a laminopathy",

abstract = "Lamin mutations cause muscular dystrophies, but the mechanism is unclear. A new study shows that lamin mutant worms display muscle-specific defects linked to altered subnuclear localization of heterochromatin, leading to altered gene expression.",

author = "Brickner, {Jason H.}",

year = "2011",

month = oct,

day = "11",

doi = "10.1016/j.cub.2011.09.006",

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T1 - Nuclear architecture

T2 - The cell biology of a laminopathy

AU - Brickner, Jason H.

PY - 2011/10/11

Y1 - 2011/10/11

N2 - Lamin mutations cause muscular dystrophies, but the mechanism is unclear. A new study shows that lamin mutant worms display muscle-specific defects linked to altered subnuclear localization of heterochromatin, leading to altered gene expression.

AB - Lamin mutations cause muscular dystrophies, but the mechanism is unclear. A new study shows that lamin mutant worms display muscle-specific defects linked to altered subnuclear localization of heterochromatin, leading to altered gene expression.

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JO - Current Biology

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Nuclear architecture: The cell biology of a laminopathy

Abstract

ASJC Scopus subject areas

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