Nuclear Pore Complexes: A Scaffold Regulating Developmental Transcription?

Atsushi Satomura, Jason H. Brickner*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as scaffolds that recruit the transcription factor Mef2C to the NPC, promoting transcription of NPC-associated genes during muscle development.

Original languageEnglish (US)
Pages (from-to)621-622
Number of pages2
JournalTrends in Cell Biology
Volume27
Issue number9
DOIs
StatePublished - Sep 2017

Keywords

  • differentiation
  • nuclear architecture
  • nuclear pore complex
  • transcription

ASJC Scopus subject areas

  • Cell Biology

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