Abstract
Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as scaffolds that recruit the transcription factor Mef2C to the NPC, promoting transcription of NPC-associated genes during muscle development.
Original language | English (US) |
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Pages (from-to) | 621-622 |
Number of pages | 2 |
Journal | Trends in Cell Biology |
Volume | 27 |
Issue number | 9 |
DOIs | |
State | Published - Sep 2017 |
Keywords
- differentiation
- nuclear architecture
- nuclear pore complex
- transcription
ASJC Scopus subject areas
- Cell Biology