Nucleic acid-modified nanostructures as programmable atom equivalents: forging a new "table of elements"

Robert J. Macfarlane, Matthew N. O'Brien, Sarah Hurst Petrosko, Chad A Mirkin

Research output: Contribution to journalReview article

105 Scopus citations


A nanoparticle-based analogue to the Periodic Table of the elements, where rather than arranging entries by electronic configuration, they are arranged by nanoscale architectural feature (e.g., composition, size, shape, and surface functionality). Using this table as a guide, the design considerations associated with using nucleic acids to assemble these nanoparticle-based programmable atom equivalents (PAEs) into superlattices is discussed.

Original languageEnglish (US)
Pages (from-to)5688-5698
Number of pages11
JournalAngewandte Chemie - International Edition
Issue number22
StatePublished - May 27 2013



  • DNA
  • colloidal crystals
  • nanomaterials
  • nanoparticles
  • programmable atom equivalents

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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